產(chǎn)品編號(hào) | bs-19699R-Gold |
英文名稱 | Rabbit Anti-QTRT1/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的鳥(niǎo)嘌呤插入酶QTRT1抗體 |
別 名 | FP3235; Guanine insertion enzyme; qtrt1; Queuine tRNA ribosyltransferase 1; Queuine tRNA ribosyltransferase; Queuine tRNA-ribosyltransferase; TGT; TGT, 43 KD subunit; TGT, catalytic subunit; TGT_HUMAN; TGUT; tRNA guanine transglycosylase; tRNA-guanine transglycosylase. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, (predicted: Human, Rat, Guinea Pig, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 44kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human QTRT1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, Feb 2012] Function: Interacts with QTRTD1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Subcellular Location: Cytoplasm. Mitochondrion. Nucleus. Weakly associates with mitochondria, possibly via QTRTD1. Similarity: Belongs to the queuine tRNA-ribosyltransferase family. Database links: Entrez Gene: 81890 Human Entrez Gene: 60507 Mouse Entrez Gene: 393985 Zebrafish Omim: 609615 Human SwissProt: Q9BXR0 Human SwissProt: Q9JMA2 Mouse SwissProt: Q7SYK1 Zebrafish Unigene: 631638 Human Unigene: 436579 Mouse Unigene: 53858 Rat Unigene: 9747 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |