產(chǎn)品編號 | bs-19494R-Gold |
英文名稱 | Rabbit Anti-NT5M/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的線粒體NT5M抗體 |
別 名 | 3''-nucleotidase; 5''; 5''(3'')-deoxyribonucleotidase; 5'(3')-deoxyribonucleotidase, mitochondrial; 5',3'-nucleotidase, mitochondrial; Deoxy-5''-nucleotidase 2; dNT-2; DNT2; mitochondrial; NT5M; NT5M_HUMAN, |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, (predicted: Human, Rat, Chicken, Pig, Cow, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 26kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NT5M |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: This gene encodes a 5' nucleotidase that localizes to the mitochondrial matrix. This enzyme dephosphorylates the 5'- and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008] Function: Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP. Subcellular Location: Mitochondrion. Tissue Specificity: Highly expressed in heart, brain and skeletal muscle. Detected at very low levels in kidney and pancreas. Similarity: Belongs to the 5'(3')-deoxyribonucleotidase family. Database links: Entrez Gene: 56953 Human SwissProt: Q9NPB1 Human Unigene: 513977 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |