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Rabbit Anti-CCBE1/Gold Conjugated antibody (bs-7985R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-7985R-Gold
英文名稱 Rabbit Anti-CCBE1/Gold Conjugated antibody
中文名稱 膠體金標記的膠原蛋白和鈣結(jié)合表皮生長因子結(jié)構(gòu)域1抗體
別    名 CCBE 1; ccbe1; CCBE1_HUMAN; Collagen and calcium binding EGF domain containing protein 1; Collagen and calcium binding EGF domains 1; Collagen and calcium-binding EGF domain-containing protein 1; Full of fluid protein homolog.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細胞生物  免疫學(xué)  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Zebrafish)
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CCBE1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene is thought to function in extracellular matrixremodeling and migration. It is predominantly expressed in theovary, but down regulated in ovarian cancer cell lines and primarycarcinomas, suggesting its role as a tumour suppressor. Mutationsin this gene have been associated with Hennekamlymphangiectasia-lymphedema syndrome, a generalized lymphaticdysplasia in humans. [provided by RefSeq, Mar 2010].

Function:
Required for lymphangioblast budding and angiogenicsprouting from venous endothelium during embryogenesis.

Subcellular Location:
Secreted (Potential).

DISEASE:
Defects in CCBE1 are the cause of Hennekamlymphangiectasia-lymphedema syndrome (HLLS) [MIM:235510]. HLLS is ageneralized lymph-vessels dysplasia characterized by intestinallymphangiectasia with severe lymphedema of the limbs, genitalia andface. In addition, affected individuals have unusual facies andsevere mental retardation.

Similarity:
Belongs to the CCBE1 family. Contains 1 EGF-like domain.

Database links:
UniProtKB/Swiss-Prot: Q6UXH8.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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