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Rabbit Anti-GNPAT/Cy5 Conjugated antibody (bs-5062R-Cy5)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-5062R-Cy5
英文名稱 Rabbit Anti-GNPAT/Cy5 Conjugated antibody
中文名稱 Cy5標(biāo)記的磷酸二羥丙酮?;D(zhuǎn)移酶抗體
別    名 DAPAT; DHAPAT; Acyl CoA dihydroxyacetonephosphateacyltransferase; DAP AT; DHAP AT; Dihydroxyacetone phosphate acyltransferase; EC 2.3.1.42; Glyceronephosphate O acyltransferase; OTTHUMP00000036147.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 38, 76kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GNPAT
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
GNPAT is a key enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in GNPAT are associated with rhizomelic chondrodysplasia punctata type 2, which is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation.

Subunit:
May be part of an heterotrimeric complex composed of DAP-AT, ADAP-S and a modified form of DAP-AT.

Subcellular Location:
Peroxisome membrane; Peripheral membrane protein; Matrix side. Note=Exclusively localized to the lumenal side of the peroxisomal membrane.

DISEASE:
Defects in GNPAT are the cause of rhizomelic chondrodysplasia punctata type 2 (RCDP2) [MIM:222765]. RDCP2 is characterized by rhizomelic shortening of femur and humerus, vertebral disorders, cataract, cutaneous lesions and severe mental retardation.

Similarity:
Belongs to the GPAT/DAPAT family.

Database links:

Entrez Gene: 8443 Human

Entrez Gene: 14712 Mouse

Omim: 602744 Human

SwissProt: O15228 Human

SwissProt: P98192 Mouse

Unigene: 498028 Human

Unigene: 29114 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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