| 產(chǎn)品編號 | IHC0462H |
| 英文名稱 | Human Lamin B2 Ready-To-Use IHC Kit |
| 中文名稱 | 人核纖層蛋白B2即用型免疫組化試劑盒 |
| 別 名 | EPM9; LAMB2; lamin-B2; LMN2; LMNA; LMNB2; RGD1563803; Lamin B2 |
| 克 隆 號 | |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial lipodystrophy. In addition, the expression of A-type lamins coincides with cell differentiation and as A-type lamins specifically interact with chromatin, a role in the regulation of differential gene expression has been suggested for A-type lamins. SWISS: Q03252 Gene ID: 84823 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human spleen tissue slide using IHC0462H (Human Lamin B2 IHC Kit).
Immunohistochemical analysis of paraffin embedded human brain tissue slide using IHC0462H (Human Lamin B2 IHC Kit).
Immunohistochemical analysis of paraffin embedded human testis tissue slide using IHC0462H (Human Lamin B2 IHC Kit).
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