| 產(chǎn)品編號 | bs-24625R |
| 英文名稱 | LASS3 Rabbit pAb |
| 中文名稱 | 長壽相關(guān)基因lASS3抗體 |
| 別 名 | LAG1 longevity assurance homolog 3; CerS3; LAG1 homolog, ceramide synthase 3; LASS 3; MGC 27091; CERS3_HUMAN. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應(yīng) | Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 46 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse LASS3: 301-3893/383 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
LASS3 is a 383 amino acid membrane protein almost exclusively expressed in testis, suggesting that LASS3 plays an important role in proper testis function. It is also weakly expressed in skin. A transcriptional variant of LASS3 cDNA exists and can result in the production of a 419 amino acid protein (LASS3-long). LASS3 overproduction raises the level of several ceramide species, including C18:0- and C24:0-ceramides. Function: May be involved in sphingolipid synthesis or its regulation Subcellular Location: Nucleus membrane; Multi-pass membrane protein Similarity: Contains 1 homeobox DNA-binding domain. Contains 1 TLC (TRAM/LAG1/CLN8) domain. Gene ID: 545975 Database links: Entrez Gene: 204219 Human Entrez Gene: 545975 Mouse SwissProt: Q8IU89 Human Unigene: 662371 Human |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Testis (Mouse) Tissue Lysate at 40 ug
Lane 2: Testis (Rat) Tissue Lysate at 40 ug
Lane 3: Ear (Rat) Tissue Lysate at 40 ug
Lane 4: Esophagus (Rat) Tissue Lysate at 40 ug
Primary: Anti-LASS3 (bs-24625R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kD
Observed band size: 46 kD
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