| 產(chǎn)品編號(hào) | bsm-63104R |
| 英文名稱(chēng) | phospho-DNA PKcs (S2056) Recombinant Rabbit mAb |
| 中文名稱(chēng) | 磷酸化DNA依賴(lài)性蛋白激酶重組兔單抗 |
| 別 名 | DNA- PKcs; DNA-dependent protein kinase catalytic subunit; DNPK1; EC 2.7.11.1; P460; PRKD; PRKDC; XRCC7; kinase DNA-PK. |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Recombinant |
| 克 隆 號(hào) | 8A8 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:50-1:200,ICC/IF=1:50-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 469 kDa |
| 檢測(cè)分子量 | 469 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human DNA PKcs around the phosphorylation site of S2056: YS-pS-QD |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. SWISS: P78527 Gene ID: 5591 DNA依賴(lài)的蛋白激酶(DNA-PK)是一種DNA活化的核絲氨酸蘇氨酸蛋白激酶. 參與體內(nèi)DNA雙鏈斷裂缺口的修復(fù), 在腫瘤的預(yù)后、發(fā)生、發(fā)展、診斷和治療等研究中引起科研人員越來(lái)越多的重視。 |
