| 產(chǎn)品編號(hào) | bs-19401R |
| 英文名稱 | PROX2 Rabbit pAb |
| 中文名稱 | PROX2蛋白抗體 |
| 別 名 | Homeobox prospero-like protein PROX2; Prospero homeobox protein 2; PROX-2; PROX2; PROX2_HUMAN. |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 66 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PROX2: 501/592/592 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Uroguanylin is an endogenous activator of intestinal guanylate cyclase. It is a paracrine and/or autocrine regulator of intestinal water and salt transport. Uroguanylin stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Uroguanylin is involved in the regulation of intestinal fluid and electrolyte transport. Function: Transcription regulator. Does not seem to be essential for embryonic development and postnatal survival. Subcellular Location: Nucleus. Similarity: Belongs to the Prospero homeobox family. Contains 1 Prospero-type homeobox DNA-binding domain. SWISS: Q3B8N5 Gene ID: 283571 Database links: Entrez Gene: 283571 Human SwissProt: Q3B8N5 Human Unigene: 675293 Human |
| 產(chǎn)品圖片 |
Sample:
Uterus (Mouse) Lysate at 40 ug
Primary: Anti-PROX2 (bs-19401R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 66 kD
Observed band size: 66 kD
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