| 產(chǎn)品編號(hào) | bs-18618R |
| 英文名稱(chēng) | MAGEA6 Rabbit pAb |
| 中文名稱(chēng) | 黑色素瘤相關(guān)抗原6抗體 |
| 別 名 | Cancer/testis antigen 1.6; Cancer/testis antigen family 1, member 6; CT1.6; MAGA6_HUMAN; MAGE 3b; MAGE 6 antigen; MAGE-6 antigen; MAGE3B; MAGE3B antigen; MAGE6; MAGEA6; Melanoma antigen family A 6; Melanoma associated antigen 6; Melanoma-associated antigen 6. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | (predicted: Human, Cynomolgus Monkey) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 35 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MAGEA6: 231-314/314 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] Tissue Specificity: Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Similarity: Contains 1 MAGE domain. SWISS: Q6NW44 Gene ID: 4105 Database links: Entrez Gene: 4105 Human Entrez Gene: 17142 Mouse Omim: 300176 Human SwissProt: P43360 Human SwissProt: Q6NW44 Human Unigene: 441113 Human Unigene: 377098 Mouse |
