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KLC3 Rabbit pAb (bs-16751R)  
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產(chǎn)品編號 bs-16751R
英文名稱 KLC3 Rabbit pAb
中文名稱 驅(qū)動蛋白輕鏈3抗體
別    名 Kinesin light chain 2; Kinesin light chain 3; KLC2; KLC2 like; KLC2-like; KLC2L; KLC3; KLC3_HUMAN; KLCt; KNS2B.  
研究領(lǐng)域 細(xì)胞生物  發(fā)育生物學(xué)  信號轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Rat (predicted: Human,Mouse,Cow,Horse, Orangutan)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 55 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KLC3: 401-504/504 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria. [provided by RefSeq, Jul 2008]

Function:
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.

Subcellular Location:
Cytoplasm > cytoskeleton. Elongating spermatid tail midpiece, localized in outer dense fibers (ODFs) and associates with mitochondria.

Similarity:
Belongs to the kinesin light chain family.
Contains 5 TPR repeats.

SWISS:
Q6P597

Gene ID:
147700

Database links:

Entrez Gene: 147700 Human

Entrez Gene: 517633 Cow

Entrez Gene: 232943 Mouse

Entrez Gene: 100173098 Orangutan

Entrez Gene: 171549 Rat

Omim: 601334 Human

SwissProt: Q2TBQ9 Cow

SwissProt: Q6P597 Human

SwissProt: Q91W40 Mouse

SwissProt: Q5R8E2 Orangutan

SwissProt: Q68G30 Rat

Unigene: 298079 Human

Unigene: 213403 Mouse

Unigene: 161815 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (rat stomach tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (KLC3) Polyclonal Antibody, Unconjugated (bs-16751R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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