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SLC35C2 Rabbit pAb (bs-12118R)  
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產品編號 bs-12118R
英文名稱 SLC35C2 Rabbit pAb
中文名稱 溶質載體蛋白家族35成員C2抗體
別    名 BA394O2.1; C20orf5; CGI-15; FLJ37039; MGC20633; MGC32079; MGC39183; Ovarian cancer-overexpressed gene 1 protein; OVCOV1; S35C2_HUMAN; SLC35C2; Solute carrier family 35 member C2.  
研究領域 腫瘤  心血管  細胞生物  神經生物學  信號轉導  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human,Mouse,Rat (predicted: Rabbit,Pig,Sheep,Cow,Chicken,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 40 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC35C2: 81-200/365 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 SLC35C2 (solute carrier family 35, member C2), also known as C20orf5, OVCOV1 or CGI-15, is a 365 amino acid multi-pass membrane protein that belongs to the TPT transporter family and exists as multiple alternatively spliced isoforms. Expressed ubiquitously and functionally induced in hypoxic trophoblast cells, SLC35C2 plays a role in the cellular response to tissue hypoxia and is thought to be involved in the pathogenesis of ovarian cancer. The gene encoding SLC35C2 maps to human chromosome 20, which houses over 600 genes some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.

Function:
May play an important role in the cellular response to tissue hypoxia.

Subcellular Location:
Membrane.

Tissue Specificity:
Ubiquitously expressed although the level of expression is tissue dependent. Overexpressed in ovarian cancer.

Similarity:
Belongs to the TPT transporter family. SLC35C subfamily.

SWISS:
Q9NQQ7

Gene ID:
51006

Database links:

Entrez Gene: 514485 Cow

Entrez Gene: 609863 Dog

Entrez Gene: 100056733 Horse

Entrez Gene: 51006 Human

Entrez Gene: 228875 Mouse

Entrez Gene: 100152375 Pig

Entrez Gene: 100349356 Rabbit

Entrez Gene: 311637 Rat

Entrez Gene: 323482 Zebrafish

SwissProt: Q9NQQ7 Human

SwissProt: Q8VCX2 Mouse

Unigene: 593344 Human



產品圖片
Sample: Lane 1: Mouse Liver tissue lysates Lane 2: Mouse Cerebrum tissue lysates Lane 3: Rat Large intestine tissue lysates Lane 4: Rat Cerebrum tissue lysates Primary: Anti-SLC35C2 (bs-12118R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kDa Observed band size: 48 kDa
Sample: A549 Cell (Human) Lysate at 30 ug Primary: Anti-SLC35C2 (bs-12118R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kD Observed band size: 40 kD
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