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cIAP1 Rabbit pAb (bs-4262R)  
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產(chǎn)品編號(hào) bs-4262R
英文名稱 cIAP1 Rabbit pAb
中文名稱 凋亡抑制因子1抗體
別    名 API 1; API1; Apoptosis inhibitor 1; Baculoviral IAP repeat containing 2; Baculoviral IAP repeat containing protein 2; Baculoviral IAP repeat-containing protein 2; BIRC 2; BIRC2; BIRC2_HUMAN; C IAP1; C-IAP1; cIAP 1; HIAP 2; HIAP-2; HIAP2; IAP 2; IAP homolog B; IAP-2; IAP2; Inhibitor of apoptosis protein 2; MIHB; NFR2 TRAF signalling complex protein; RING finger protein 48; RNF 48; RNF48; TNFR2 TRAF signaling complex protein 2; TNFR2-TRAF-signaling complex protein 2.  
Specific References  (3)     |     bs-4262R has been referenced in 3 publications.
[IF=5.988] He Shanqing. et al. Dapagliflozin Protects Methamphetamine-Induced Cardiomyopathy by Alleviating Mitochondrial Damage and Reducing Cardiac Function Decline in a Mouse Model. FRONT PHARMACOL. 2022 Jul;0:2578  WB ;  Mouse.  
[IF=2.91] Sun et al. Mechanisms underlying 3-bromopyruvate-induced cell death in colon cancer. (2015) J.Bioenerg.Biomembr. 47:319-29  WB ;  Mouse.  
[IF=1.69] Xuan et al. Short?term vagus nerve stimulation reduces myocardial apoptosis by downregulating microRNA?205 in rats with chronic heart failure. (2017) Mol.Med.Rep. 16:5847-5854  WB ;  Rat.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  細(xì)胞凋亡  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Mouse,Rat (predicted: Human)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 72 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human cIAP1: 51-150/618 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).

SWISS:
Q13490

Gene ID:
329

Database links:

Entrez Gene: 329 Human

Entrez Gene: 11797 Mouse

Entrez Gene: 60371 Rat

Omim: 601712 Human

SwissProt: Q13490 Human

SwissProt: Q62210 Mouse

Unigene: 696238 Human

Unigene: 335659 Mouse

Unigene: 205955 Rat



產(chǎn)品圖片
Sample: Lane 1: Mouse Testis tissue lysates Lane 2: Rat Testis tissue lysates Primary: Anti-cIAP1 (bs-4262R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 72 kDa Observed band size: 61,72 kDa
Paraformaldehyde-fixed, paraffin embedded (mouse testis tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (cIAP1) Polyclonal Antibody, Unconjugated (bs-4262R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Paraformaldehyde-fixed, paraffin embedded (rat heart tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (cIAP1) Polyclonal Antibody, Unconjugated (bs-4262R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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