| 產品編號 | bs-3966R |
| 英文名稱 | PPM2C Rabbit pAb |
| 中文名稱 | 蛋白磷酸酶2C抗體 |
| 別 名 | PDH; PDP 1; PDP; PDP1; PDPC 1; PDPC; Protein phosphatase 2C; protein phosphatase 2C, magnesium dependent, catalytic subunit; Pyruvate dehydrogenase phosphatase, catalytic subunit 1; PDP1_HUMAN. |
| 研究領域 | 腫瘤 細胞生物 免疫學 信號轉導 細胞凋亡 轉錄調節(jié)因子 激酶和磷酸酶 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | Dog (predicted: Human,Mouse,Rat,Rabbit,Cow,Horse) |
| 產品應用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 52 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PPM2C: 51-150/537 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
PPM2C is a protein similar to members of the protein phosphatase 2C (PP2C) family. It is a catalytic subunit of the mitochondrial matrix phosphatase and is involved in reactivation of the pyruvate dehydrogenase complex. Function: Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex (By similarity). Subunit: Heterodimer of a catalytic (PDP1) and a regulatory (PDPR) subunit (By similarity). Subcellular Location: Mitochondrion matrix (By similarity). DISEASE: Defects in PDP1 are the cause of pyruvate dehydrogenase phosphatase deficiency (PDP deficiency) [MIM:608782]. PDP deficiency results in lactic acidosis leading to neurological dysfunction. Similarity: Belongs to the PP2C family. SWISS: Q9P0J1 Gene ID: 54704 Database links: Entrez Gene: 54704 Human Entrez Gene: 381511 Mouse Omim: 605993 Human SwissProt: Q9P0J1 Human SwissProt: Q3UV70 Mouse Unigene: 22265 Human Unigene: 331489 Mouse Unigene: 31799 Rat |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
