| 產(chǎn)品編號(hào) | bs-3683R |
| 英文名稱(chēng) | NADPH oxidase 3 Rabbit pAb |
| 中文名稱(chēng) | NADPH oxidase 3抗體 |
| 別 名 | Mitogenic oxidase 2; MOX 2; MOX2; NADPH oxidase 3; NADPH oxidase catalytic subunit-like 3; NOX 3; NOX3; GP91 3; GP91-3; gp91phox homolog 3. |
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Specific References (4) | bs-3683R has been referenced in 4 publications.
[IF=9.83] Wakatsuki, Shuji, et al. "Oxidative stress–dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration." The Journal of cell biology(2015): jcb-201506102. IHC-P ; Mouse.
[IF=5.33] Shuji Wakatsuki. et al. Selective phosphorylation of serine 345 on p47-phox serves as a priming signal of ROS-mediated axonal degeneration. Exp Neurol. 2022 Jun;352:114024 WB ; Mouse.
[IF=4.011] Kim YR et al. Identification of highly potent and selective inhibitor, TIPTP, of the p22phox-Rubicon axis as a therapeutic agent for rheumatoid arthritis. Sci Rep. 2020 Mar 12;10(1):4570. IP ; mouse.
[IF=3.448] Ma Q et al. Non‐coenzyme role of vitamin B1 in RANKL‐induced osteoclastogenesis and ovariectomy induced osteoporosis. J Cell Biochem. 2020 Feb 26. WB ; mouse.
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| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 激酶和磷酸酶 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 65 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Nox3/NADPH oxidase 3: 65-160/568 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation. The protein encoded by this gene is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. SWISS: Q9HBY0 Gene ID: 50508 Database links: Entrez Gene: 50508 Human Entrez Gene: 224480 Mouse Omim: 607105 Human SwissProt: Q9HBY0 Human SwissProt: Q672J9 Mouse Unigene: 247776 Human Unigene: 328756 Mouse Unigene: 161761 Rat |
