| 產(chǎn)品編號 | bsm-62848R |
| 英文名稱 | Phospho-Syk(Tyr323) Recombinant Rabbit mAb |
| 中文名稱 | 磷酸化非受體型酪氨酸蛋白激酶重組兔單抗 |
| 別 名 | KSYK; p72syk; Spleen tyrosine kinase; Syk. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:50-1:200,ICC/IF=1:50-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 72 kDa |
| 檢測分子量 | 72 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human Syk around the phosphorylation site of Y323: FNP-pY-EPE |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development.Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. SWISS: P43405 Gene ID: 6850 受體型酪氨激酶蛋白（ＰＴＫ）介導(dǎo)的信號傳遞在Ｔ細(xì)胞，Ｂ細(xì)胞，ＮＫ細(xì)胞和粒細(xì)胞激活的過程中發(fā)揮著重要作用，其基因結(jié)構(gòu)或基因表達(dá)的異常是某些免疫缺陷性疾病和免疫增殖性疾病的發(fā)生原因。 |
