| 產(chǎn)品編號(hào) | bsm-62144R |
| 英文名稱(chēng) | MAG Recombinant Rabbit mAb |
| 中文名稱(chēng) | 髓鞘相關(guān)糖蛋白-a重組兔單抗 |
| 別 名 | GMA; MAG; S MAG; SIGLEC4A; SPG75. |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Recombinant |
| 克 隆 號(hào) | 11H8 |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:500-1:2000,Flow-Cyt=1:20-1:100,IP=1:20-1:50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 69 kDa |
| 檢測(cè)分子量 | 100 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human MAG: 50-100/626 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3-linked sialic acid. SWISS: P20916 Gene ID: 4099 髓鞘相關(guān)糖蛋白a/b（MAG-a/b）又稱(chēng)：髓磷脂相關(guān)的球蛋白 髓鞘相關(guān)糖蛋白(myelin-associated glycoprotein, MAG)是免疫球蛋白超家族成員，它由中樞神經(jīng)系統(tǒng)的少突膠質(zhì)細(xì)胞和外周神經(jīng)系統(tǒng)的施萬(wàn)細(xì)胞表達(dá)。 MAG定位于直接和軸突相接觸的髓鞘膜的最里層，它通過(guò)介導(dǎo)膠質(zhì)細(xì)胞與軸突的相互作用參與髓鞘的形成及其完整性的維持。同時(shí)MAG也是髓鞘來(lái)源的神經(jīng)生長(zhǎng)抑制因子的主要成分。在神經(jīng)系統(tǒng)發(fā)育的不同階段，MAG顯示不同的功能:即發(fā)育期促進(jìn)軸突生長(zhǎng)，成熟期抑制軸突生長(zhǎng)。其抑制作用主要由髓 |
| 產(chǎn)品圖片 |
25 ug total protein per lane of various lysates (see on figure) probed with MAG monoclonal antibody, unconjugated (bsm-62144R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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