| 產(chǎn)品編號(hào) | bsm-62027R |
| 英文名稱 | RAP1GAP Recombinant Rabbit mAb |
| 中文名稱 | RAP1 GTP酶激活蛋白重組兔單抗 |
| 別 名 | RAP1GA1; Rap1GAP; Rap1GAP1; RAP1GAPII; RAPGAP. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | IHC-P=1:50-200,IHC-F=1:50-200,IF=1:50-200,Flow-Cyt=1:20-50,ICC/IF=1:50-200,IP=1:20-50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 73 kDa |
| 檢測(cè)分子量 | 95 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human Rap1GAP: 5-40 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. SWISS: P47736 Gene ID: 5909 RaplGAP在細(xì)胞的粘附連接及形成過程中所發(fā)揮著一定作用。RaplGAP是小分子G蛋白R(shí)apl的GTP酶激活蛋白(GTPase activating protein)，它可以加速rap1由活化形式(與GTP結(jié)合)轉(zhuǎn)變?yōu)槿セ罨问?與GDP結(jié)合)。由于粘附連接的破壞或延遲了粘附連接形成的過程，對(duì)腫瘤轉(zhuǎn)移有著密切的聯(lián)系。 |
